A study of emergency care involving victims of severe traumatic brain injury is to be performed in this area. The University of lowa Hospitals & Clinics is conducting a research study to identify the best way to deliver high dose oxygen under pressure (hyperbaric oxygen) so that severe Traumatic Brain Injury (TBI) patients can recover with less disability. All patients will receive standard of care for their TBI. Because head injury is a life threatening condition requiring immediate treatment, some patients will be enrolled without consent if a family member or representative is not rapidly available. Before the study starts, we will consult with the community. We welcome your feedback and questions. For more information or to decline participation in this study, please visit: hobittrial.org or contact our study staff at EM-Research@uiowa.edu Primary Investigator: Dr. Nicholas Mohr, MD Study Coordinator: Catherine Fairfield THE UNIVERSITY OF IOWA HO,BIT A study of emergency care involving victims of severe traumatic brain injury is to be performed in this area. The University of lowa Hospitals & Clinics is conducting a research study to identify the best way to deliver high dose oxygen under pressure (hyperbaric oxygen) so that severe Traumatic Brain Injury (TBI) patients can recover with less disability. All patients will receive standard of care for their TBI. Because head injury is a life threatening condition requiring immediate treatment, some patients will be enrolled without consent if a family member or representative is not rapidly available. Before the study starts, we will consult with the community. We welcome your feedback and questions. For more information or to decline participation in this study, please visit: hobittrial.org or contact our study staff at EM-Research@uiowa.edu Primary Investigator: Dr. Nicholas Mohr, MD Study Coordinator: Catherine Fairfield THE UNIVERSITY OF IOWA HO,BIT